Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors in the central nervous process, conolidine modulates alternate molecular targets. A Science Improvements analyze uncovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By inf... https://conolidine-for-pain-relie86344.blogdon.net/the-fact-about-conoldine-alternative-natural-pain-relief-that-no-one-is-suggesting-54683687