Spindle poison-based therapy is of only limited benefit in acute myeloid leukemia while lymphoblastic leukemia/lymphoma responds well. In this study. we demonstrated that the spindle assembly checkpoint protein BubR1 was down-regulated in the vast majority of cases of acute myeloid leukemia whereas its expression was high in lymphoblastic cells. Correct function of the spindle assembl... https://www.roneverhart.com/HP-Pavilion-15-eg2373cl-15-6-FHD-Touch-Laptop-Intel-Core-i7-1255U-3-50-GHz-GeForce-MX550-16GB-DDR4-512GB-SSD-Windows--p8309/