As a way to rationalise the noticed ABL kinase inhibitory final results from the 3D structural standpoint, the lead compounds I and II, as well as freshly made derivatives 4a, 4b, and 5 were docked from the catalytic kinase domains of BCR-ABLWT (PDB code: 3OXZ) and BCR-ABLT315I (PDB code: 3OY3)34. https://simonvpizp.daneblogger.com/30450034/indazole-3-carboxamide-an-overview