Sedative medicines including benzodiazepines or related medicines: The concomitant usage of opioids with sedative medicines like benzodiazepines or linked medication enhances the danger of sedation, respiratory depression, coma and Dying because of additive CNS depressant impact. The dose and period of concomitant use need to be minimal (see portion four.4). https://seymourh098xbc0.wikilowdown.com/user