TL;DR: The use of brown alga (Bifurcaria bifurcata) during the biosynthesis of copper oxide nanoparticles of dimensions five–forty five nm is claimed for The 1st time and these nanoparticles were being uncovered to exhibit higher antibacterial activity versus two various strains of microbes. Afterward, in 1991, Drexler, Peterson and Pergamit https://www.directivepublications.org/journal-of-applied-nanoscience/